Opana ER (Oxymorphone)


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Oxymorphone is an opioid medicine that is used to treat moderate to severe pain. The extended-release form of oxymorphone is for around-the-clock treatment of pain and should not be used on an as-needed basis for pain. Oxymorphone may also be used for purposes not listed in this medication guide.

What is Opana?

Opana is the trade name for oxymorphone, which is a powerful opioid analgesic. Oxymorphone is twice as strong as oxycodone (the active ingredient in Oxycontin), and approximately 6-8 times more potent than morphine. Yes, it’s a Schedule II controlled substance for a reason.

Users can currently choose from two different types of Opana: the immediate release version (simply called Opana), and the newer formula, the extended release version (Opana ER). Opana ER is often prescribed for patients who need a consistent amount of the drug delivered to their systems within 24 hours, but the extended release version can deliver a potent high when it is crushed and then injected or snorted.

Opana Side Effects

Because it is derived from the opiate family, Opana is particularly dangerous when taken with alcohol. The combination of those two drugs can increase plasma levels, creating a potentially life-threatening scenario. Opiates have also been known to negatively affect the respiratory system, creating a condition (respiratory depression) where breathing drops below the normal rate.

Opana is also known to impair your thinking and reasoning.

Call your doctor if you experience any of the following seizure symptoms:

  • Shallow breathing
  • Weakness or dizziness
  • Feeling lightheaded or faint
  • Seizures

Overdoses to Opana can trigger apnea, cardiac arrest, or death.

The Generic Version: Oxymorphone

When the newer (more tamper-resistant) version of Opana ER was released in December 2011,  a generic form of Opana, called Oxymorphone ER was approved (7.5 mg and 15 mg) and will be available September 2012. Generics for the newer formula strengths will probably not be available until 2023 when first patent expires.

Where Do You Get Opana

Right now, Opana is a prescription painkiller and should be taken only under medical supervision. Even under those circumstances, the drug could trigger a respiratory depression or create a potentially fatally overdose if taken with alcohol.

Qty Pills

5mg(60pills), 5mg(120pills), 5mg(180pills), 5mg(240pills), 10mg(60pills), 10mg(120pills), 10mg(180pills), 10mg(240pills), 15mg(60pills), 15mg(120pills), 15mg(180pills), 15mg(240pills), 20mg(60pills), 20mg(120pills), 20mg(180pills), 20mg(240pills), 40mg(60pills), 40mg(120pills), 40mg(180pills), 40mg(240pills)


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